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Over time, they have also proven to be highly effective for weight loss
After reviewing this study, Anton Bilchik, MD, PhD, surgical oncologist, chief of medicine, and director of the Gastrointestinal and Hepatobiliary Program at Providence Saint Johns Cancer Institute in Santa Monica, CA, not involved in the research, told MNT this was one of the most provocative, interesting studies he has seen in a long time simply because there has been an explosion of interest and use of GLP-1 agonist drugs such as Ozempic and Mounjaro
HRT replenishes declining hormones like estrogen and progesterone during menopause
Protein supplementation combined with resistance training leads to greater preservation of lean mass and strength than training alone. Key point: With adequate protein intake and resistance training, patients can maintainand sometimes increasestrength during GLP-1 therapy despite overall weight loss. Recovery and micronutrients Adequate sleep, hydration, and correction of deficiencies (including vitamin D when present) further support muscle function and recovery. Bottom Line: GLP-1 Medications Improve Body Composition Not Muscle Wasting Semaglutide and tirzepatide do not inherently cause muscle wasting. Most weight lost is fat , and body composition improves. Muscle wasting is primarily a risk of undernutrition , not GLP-1 therapy itself. Protein + resistance training is the most effective strategy to preserve muscle. At Potere Health MD, GLP-1 and GIP therapy is paired with evidence-based nutrition and strength guidance so weight loss is healthier, stronger, and more sustainable
This pattern fits with the fact that central GLP-1 can inhibit feeding behaviours independently from GLP-1-gut-brain signalling 7
Kitzman DW, Brubaker P, Morgan T et al (2016) Effect of caloric restriction or aerobic exercise training on peak oxygen consumption and quality of life in obese older patients with heart failure with preserved ejection fraction: a randomized clinical trial
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