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The study demonstrated that in spontaneously hypertensive rats, liraglutide reduced circulating Ang II levels, upregulated cardiac angiotensin II type 2 receptor (AT2R) and angiotensin-converting enzyme-2 (ACE2) expression, and attenuated myocardial hypertrophy [145]

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Intracellular accumulation of 125 I-semaglutide declined after removal of the donor medium, resulting in a 66% reduction in the accumulated compound after 15 minutes

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