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278,279 Lifestyle interventions, particularly aerobic exercise, have also demonstrated benefits in enhancing mitochondrial biogenesis and function, offering a non-pharmacological approach to managing DPN (Fig

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After 24 h, medium was replaced with DMEM/FBS/15 g ml 1 blasticidin/100 g ml 1 hygromycin (DMEM/FBS/B/H), followed by selection for approximately 2 weeks (medium change every 3 d)

doi:10.1007/s00018-008-8516-1