glp-1 amgen GIPR antagonist antibodies conjugated to peptide are bispecific molecules that decrease weight in obese mice and monkeys: Cell Reports Medicine 2025’s Breakthrough GLP-1 Obesity Treatments:

Endres LK, Straub H, McKinney C, Plunkett B, Minkovitz CS, Schetter CD, et al

The medication helps you feel full sooner, which leads to a reduction in food intake

[1] [9] In the central nervous system, these medications act on appetite-regulating centers to reduce hunger and increase satiety, contributing to weight loss

While this basic understanding is helpful it doesnt really tell you which is the right choice for you

Verify actual cost-share on Highmark's member portal or with your pharmacist before starting treatment

19-25 Table 4 provides a summary of key warnings and precautions listed in the labeling of each GLP-1 RA product that should be taken into account when considering use in a patient with T2D