Our body breaks down GLP-1 so quickly that it hardly makes it even one time around our circulatory system, which is why we cant just take the hormone directly
Accordingly, leptin increases insulin sensitivity, specifically insulin-stimulated glucose utilization or glucose oxidation in skeletal muscle and BAT, but this is blunted in WAT [126]
Take it before or after meals
Note that not every multivitamin contains all of these nutrients
For injectable GLP-1 medications, timing relative to levothyroxine is less critical since the interaction occurs through general effects on gastric emptying rather than direct simultaneous absorption
"People can collapse, have seizures and, if they don't get medical attention, organ failure and prolonged damage