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By performing k-medoid clustering on the normalized HTO values, k (number of samples) +1 clusters were obtained, and some clusters were defined as negative cluster based on the calculated negative distribution for HTO

The drug primarily increases insulin secretion and decreases glucagon secretion in a glucose-dependent manner

In turn, the study by Xu et al

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CQDs are typically produced at milligram- to gram-scale, and attempts to scale production to kilogram levels introduces batch-to-batch variability in morphology, optical output, and surface functionality [85, 170]