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[3] [9] The mechanism of action involves binding to both GIP and GLP-1 receptors, which are naturally occurring incretin hormones

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Like Semaglutide, Tirzepatide was initially designed to treat type 2 diabetes by mimicking two key hormones: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide)

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Reconstituted retatrutide in bacteriostatic water maintains potency for approximately 28-30 days when stored properly at 2-8 degrees Celsius

GLP-1 exerts its anorectic effect in part by acting on the hunger-satiety centre located in the arcuate nucleus of the hypothalamus, and in part by delaying gastric emptying