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Participants reporting increased nicotine cravings had the shortest median duration of GLP-1 use (~ 5 months), suggesting that insufficient exposure to GLP-1 therapies may result in suboptimal behavioral outcomes

Topics include unexpected weight regain on GLP-1s, post-meal sleepiness and hypoglycemia, metabolic dysfunction despite normal labs, GLP-1 dosing strategies, and why these medications are about metabolism , not appetite suppression

Metformin (one of the most commonly prescribed medications for Type 2 diabetes) can cause diarrhea, and so can coffee, meaning there could be additive bowel effects when combining the two

And there is likely a role for oral maintenance treatments, such as liver-targeting THR agonists, and VKTXs VK2809, to manage fibrosis

reported two cases of depression associated with the use of semaglutide 19

Individual timelines vary, and healthcare provider guidance helps set realistic expectations based on specific goals and circumstances