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Methods A targeted literature search of experimental and clinical studies was performed, focusing on angiogenesis-related mechanisms in neurodegeneration and the effects of antiangiogenic compounds on neuronal and vascular function

As-needed protocol: Use DSIP only during periods of elevated stress or sleep difficulty Maintain for 2-4 weeks as needed Discontinue when sleep normalizes This conservative approach treats DSIP as a targeted intervention rather than ongoing supplementation

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Eat prebiotic foods

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Med Spas, Research use online products, and compounding pharmacies are the top 3 reported access channels