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Iron overload robustly induced hepatic tissue inflammation by upregulating IL-6, IL-1, and TNF- mRNA expression, while theaflavins supplementation remarkably attenuated iron overload induced hepatic tissue inflammation by downregulating IL-6, IL-1, and TNF- mRNA expression (Fig

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NEJM Coskun T, Urva S, Roell WC, et al

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We recommend taking our suppository at bedtime 2/3 hours after your final meal, giving your body time to empty bowels if need be