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Cd38 -positive senescent cells have declined NAD + levels and mitochondrial dysfunction 18,19 and Cd38-knockout mice exhibit higher NAD + levels and are safeguarded against obesity and metabolic syndrome 72

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Commonly examined in studies involving cellular signalling and metabolic response pathways

Crucial for adaptive immunity (targeting a specific pathogen)

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This process plays a central role in the transduction of signals induced by abiotic stresses, hormones, and pathogens, while integrating environmental and developmental cues (Yang et al