[10] It is believed that the mechanism behind the potential appetite-stimulating effect of GHRP-2 mainly involves its interaction with the growth hormone secretagogue receptor (GHSR), particularly GHSR-1a
4 Orforglipron continues to demonstrate notable glycemic and weight effects in phase II trials
Its mechanism of action is based on mimicking the body's own GLP-1 hormone, which stimulates insulin secretion, reduces appetite, and slows gastric emptying
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