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121 Treatment with CRMs has been found to decrease the concentration of free IGF-1, promote autophagy in cancer cells, and improve the antitumor immune response, resulting in a reduction in tumor growth when combined with immunogenic chemotherapeutics

[DOI] [PubMed] [Google Scholar] 65.Doi K., Leelahavanichkul A., Yuen P.S., Star R.A

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Finally, N-acetylation of this conjugate by the enzyme N-acetylase yields S-substituted-N-acetyl cysteine products called as mercapturic acids