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They slow gastric emptying, increase feelings of fullness, and reduce hunger signals to the brain, leading to reduced calorie intake and subsequent weight loss
Providers titrate doses gradually to minimize side effects during the adjustment period
Fei LW, Wang Y, Chen SX (2009) Improved glutathione production by gene expression in Pichia pastoris
However, in a retrospective cohort study of electronic health records of 240,618 patients with overweight or obesity who were prescribed semaglutide or non-GLP-1 receptor agonist antiobesity medication and 1,589,855 patients with type 2 diabetes prescribed semaglutide or non GLP-1 receptor agonist hypoglycaemic treatment, during six-month follow up after initiation of treatment, there was lower risk of suicidal ideation in patients prescribed semaglutide regardless of whether there was a history of previous suicidal ideation
Key Takeaways Weight loss injections work by mimicking or stimulating gut hormones, leading to feelings of fullness and reduced appetite
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