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When excess gas builds up in the digestive tract, it creates abdominal pressure that may radiate toward the spine and cause back pain

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doi: 10.1038/s41598-024-55423-9 298 PrudentM.GiraultH

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The nuclear factor erythroid 2-related factor 2 ( NFE2L2 or NRF2) transcription factor is constitutively activated in many cancers and promotes a specific gene expression program involved in cellular detoxification, redox buffering, and metabolic rewiring (Cancer Genome Atlas Research, 2012