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doi: 10.1016/j.cmi.2019.03.028 129 PuelA.CypowyjS.MarodiL.AbelL.PicardC.CasanovaJ

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Naldemedine versus placebo for opioid-induced constipation (COMPOSE-1 and COMPOSE-2): two multicentre, phase 3, double-blind, randomised, parallel-group trials

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The mean amplification efficiency standard deviation (SD) was 0.995 0.011, and the mean correlation coefficient SD was 0.992 0.006