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This supply situation has driven interest in tirzepatide alternatives and in compounded formulations that may offer more reliable availability

(4) Other requirements

We established in the final rule that covered entities that choose to submit data to the 340B repository during the testing period beginning in 2026 will submit the fields specified by us on a quarterly basis to the 340B repository by a date announced in the future, which would be no sooner than 3 months after the date on which the 340B repository is available to receive submissions from covered entities

Used with that understanding, it has a sensible place

We also confirmed that suppliers who exclusively delivered MDPP services virtually via distance learning without maintaining in-person delivery capability were not permitted to furnish the Set of MDPP services because MDPP beneficiaries may elect to return to in-person services, and MDPP suppliers need to be able to accommodate their request (88 FR 79248)

RF microneedling is considered safer and more predictable for melanin-rich skin tones than ablative laser approaches, and combining it with GHK-Cu addresses both the structural deficit and the inflammatory component that often drives post-inflammatory hyperpigmentation in these patients