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In 2023, almost half of adults said they were interested in GLP-1s and 1 in 60 were prescribed a GLP-1 medication

In clinical trials, discontinuation rates due to gastrointestinal adverse effects ranged from 3-7%, indicating that whilst most patients can tolerate these symptoms, they can be sufficiently troublesome to necessitate treatment cessation in some cases

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MC3R and MC4R are expressed densely in hypothalamic nuclei and mediate energy balance, sexual desire, and arousal

Importantly, the majority of that loss came from fat mass rather than lean muscle, according to DEXA body-composition scans

Like injections, oral supplements support liver health, metabolism, and energy