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Abstract Therapeutic drug monitoring (TDM) is a clinical procedure aimed at maintaining plasma drug concentrations within a specific therapeutic range, thereby maximizing the safety and efficacy of pharmacological therapy

Unlike some earlier-generation GH secretagogues, Ipamorelin was developed specifically for its selectivitydemonstrating minimal stimulatory effect on cortisol or prolactin release at therapeutic doses in preclinical models

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Instead of adding amino acids, DES removes the first three from the N-terminus, creating a truncated 67 amino acid peptide