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The peptides therapeutic durability is further enhanced by several amino acid modifications and the attachment of a C-20 fatty di-acid via an -glutamyl spacer, which extends its half-life to roughly 7.3 days, allowing for weekly subcutaneous administration [5]

Furthermore, we also found MG treatment induces prolonged AMPK activation and suppression of AMPK improved beta cell survival

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Frssing S, Nylander M, Chabanova E, Frystyk J, Holst JJ, Kistorp C, et al

Mol Psychiatry 2013

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