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Y5R KO mice appear to drink similar amounts of alcohol as wildtype mice, suggesting that Y5R does not may a major role in AUD (Table 1

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10.1038/aps.2010.109 129 RabelinkT

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It sustains adequate redox cell signaling since a physiologic level of oxidative stress is fundamental for controlling life processes via redox signaling, but excessive oxidation causes cell and tissue damage