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Dost Ongur Editor's Note by JAMA Psychiatry Editor in Chief Dost ngr, MD, PhD: In a randomized clinical trial, semaglutide reduced hemoglobin A1c and body weight and improved physical quality of life in patients with #schizophrenia, #prediabetes, and #obesity, without negative effects on mental health status
Ling Yin, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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Vitamin C helps maintain levels of Glutathione (GSH), the body's "master antioxidant," which protects the insulin signaling pathway
These factors might reduce the positive effects of growth hormone on adult height ( While hypogonadism is the most common change in the pituitary-gonadal axis, CPP, though rare, has been documented in children with PWS and could be linked to loss-of-function variations in the MKRN3 gene at the 15q11-q13 locus (228, 229)
Although there have been no head-to-head trials yet, tirzepatide could potentially lead to more significant weight loss with a comparable safety profile to semaglutide, according to an article in Frontiners in Endocrinology
