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4.3 Neurodegenerative diseases Since individuals with DS are prone to elevated levels of oxidative stress at an early age and consequent accumulation of ROS, which are cytotoxic byproducts of normal mitochondrial metabolism, there is an insufficient defense of endogenous antioxidants

Yes, hair does go through stages of falling out, with the telogen phase being the stage when hair shedding happens naturally and regenerates

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References [1] Wilding, J