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By activating both GIP and GLP-1 receptors, tirzepatide enhances insulin secretion in a glucose-dependent manner, meaning insulin is released only when blood glucose levels are elevated

doi: 10.1016/j.jdiacomp.2020.107733 125

While our current treatments have shown significant therapeutic benefits, there still appear to be some patients who, despite aggressive therapy, good adherence, and inhaler technique, continue to have exacerbations

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