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Description

Antioxidant Defense : Protects against oxidative damage

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In anterograde regulation, proteins encoded by the nuclear genome are transferred to the mitochondria to perform functions (71), while in retrograde regulation, the signal generated from mitochondria passes into the nucleus to induce gene expression, which occurs when mitochondrial homeostasis is interrupted by hypoxia or mutation in mtDNA, or mitochondrial Ca 2+ release (72, 73)

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Effect of nonmyeloablative hematopoietic stem cell transplantation vs continued disease-modifying therapy on disease progression in patients with relapsing-remitting multiple sclerosis: a randomized clinical trial

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CHO = Chinese hamster ovary

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