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Summary of pathway regulation Table 7.2: Summary of pathway regulation

An RDP study with 40 patients investigated the effects of 300 mg Pycnogenol supplementation per day for two months on subjects with chronic venous insufficiency (CVI) ( significantly relieved swelling (64%) and heaviness (54%) in the legs of CVI patients compared to placebo (7 and 3%, respectively)

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Metformin alone promoted apoptosis in U87 and T98G cells, but had no significant effect on HEB cells

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