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Retatrutide is still undergoing Phase 3 clinical trials as a monotherapy, and MOTS-c is largely confined to preclinical studies, lacking regulatory approval as a therapeutic agent

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Ann Med 1997;29(2):95120

Baldini E, Lunghi A, and Cortesi E, et al (2020) Immune-related adverse events correlate with clinical outcomes in NSCLC patients treated with nivolumab: the Italian NSCLC expanded access program Lung Cancer 140 5964 79

Retatrutide hits metabolic receptors (GLP-1R, GIPR, GCGR)