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Some patients report noticing changes within several weeks, while others may require longer periods of monitoring and adjustment

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GIP may have central nervous system effects on energy homeostasis and body weight regulation that are additive with GLP-1

About 43% of it is found in the skeletal system, with the rest occurring in soft tissues including the liver, pancreas, kidneys, brain, and central nervous system

Alcohol can impair liver function regardless of GLP-1 therapy, and excessive intake remains a known risk factor for liver injury