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Such conditions may lead to the release of neurotrophic factors or the clearance of toxic debris, ultimately promoting neuronal survival [194]

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thus, in the AP, TH-positive cells are likely the A1 cell group that produces norepinephrine (NE)

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It says treatment starts low and steps up over several months, so early weeks may show modest changes before substantial reduction begins at higher maintenance levels

Proper habits reduce contamination risks during routine medication handling