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History of cardiovascular disease including coronary artery disease, stroke, arrhythmias, congestive heart failure and uncontrolled hypertension

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Because tirzepatide works on metabolic pathways rather than altering blood clotting or acting as a known teratogen (substances that cause birth defects), it is not restricted by blood banks in the same way other medications might be

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Some patients find that because gastric emptying is slowed, they wake up feeling uncomfortably full or slightly nauseous the next day