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2022;34(9):1234-47.e9

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But relying on the drug alone does not create the kind of durable health changes that reduce headaches and migraines in the long run

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This rise in cravings can disrupt appetite regulation even when a GLP 1 agonist is actively working to reduce hunger

Among 327 participants followed for a year after all treatment and lifestyle intervention stopped, a mean 17.3% weight loss at week 68 was followed by regain of 11.6 percentage points by week 120, leaving a net 5.6% below baseline