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3,17 Important metabolic and molecular insights into the essential metabolic role of NAD + in redox function were gained from studies on NAMPT-KO mice

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Further investigations revealed that deficiency of Pol promoted an augmented inflammatory response and macrophage pyroptosis in CIA mice (65)

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Interestingly, Chrysanthellum americanum aqueous extract reverted this alteration in the concentration of acetylcholine indicating the ameliorative property of the plant extract against memory impairment in pilocarpine-treated mice [5] [47] [48]