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The GLP-1 agonist, liraglutide, ameliorates inflammation through the activation of the PKA/CREB pathway in a rat model of knee osteoarthritis

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PMID: 34927243 Molecules ST2825, a Small Molecule Inhibitor of MyD88, Suppresses NF-B Activation and the ROS/NLRP3/Cleaved Caspase-1 Signaling Pathway to Attenuate Lipopolysaccharide-Stimulated Neuroinflammation

Conversely, modulating the composition of the microbiota using the probiotic VLS#3, stimulated production of butyrate, promoting GLP-1 secretion, and improving the metabolic state in mice (193)