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Monitoring considerations include: Regular assessment of gastrointestinal tolerability and hydration status Evaluation of any changes in MS symptoms, with low threshold for neurological consultation Glucose monitoring in diabetic patients, with adjustment of other antihyperglycemic agents as needed Periodic assessment of weight loss progress and nutritional adequacy Monitoring for signs of pancreatitis (severe abdominal pain) or gallbladder disease For Wegovy patients, monitoring for depression or suicidal thoughts Patient counseling should address realistic expectations regarding weight loss (typically 15% of body weight over 68 weeks with the 2.4 mg dose plus lifestyle intervention, with less at earlier timepoints), the chronic nature of therapy, and the importance of lifestyle modifications
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7 The evolving public perception of obesity and food addiction As the success of GLP-1RAs in treating overweight and obesity rises, it prompts reflection on how these pharmacological advances could reshape both public and professional perspectives
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