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Sheer and colleagues reviewed electronic health record data from 26,408 adults treated in the OneFlorida+ network from 2014 to 2024, covering 14 healthcare organizations across Florida, Georgia, and Alabama

Primary research applications include Alzheimer's disease, vascular dementia, age-related cognitive decline, and neurological recovery after brain injury

Accurate, though weight loss is modest compared to GLP-1 RAs (typically 24 kg)

Unlike PDE5 inhibitors, MT-2 enhances desire and arousal (central mechanism), not just blood flow

Bariatric surgery has decades of long-term outcome data behind it and can be life-changing, though it carries surgical risks and permanent changes to the digestive system

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