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however, aggregates of TTR, including oligomeric forms, have previously been linked to cytotoxicity [81,82,83,84,85] supporting the possibility that misfolded TTR may contribute to this response

2019;63(2): e1800962

However, newer delivery methods have shifted this conversation significantly

In yet another aspect, the invention provides methods of preventing weakness in a patient with Parkinson's disease and/or of improving or restoring muscle strength of a patient with Parkinson's disease