This balance influences numerous redox-regulated cellular processes, including the modulation of signaling pathways, post-translational modifications such as protein glutathionylation, activation of transcription factors like Nrf2 and NF-B, and the regulation of cell fate decisions such as proliferation or apoptosis [38]
Oxidized glutathione (GSSG) has no antioxidant or detoxification capacity your body can convert GSSG back to GSH using glutathione reductase and NADPH, but this process competes with endogenous glutathione recycling and provides no net benefit over baseline
Wilkinson DJ, Smeeton NJ, Watt PW
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Modern medicine has provided solutions to diseases and ailments that were thought to be impossible to cure or manage just a century ago
Since there is no effective treatment for AD in modern medicine, and since the prevalence of AD is positively correlated with an individuals age, the risk of AD can be effectively reduced by delaying or mitigating the negative effects on the nervous system that are associated with the aging process (Goedert, 2015)