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The point is that none of them are

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Clinical trials that demonstrated significant weight loss included structured dietary counseling and exercise recommendations as part of the protocol

SEM also exhibits the ability to alleviate tau pathology in the same hippocampal CA3 region, suggesting a potential influence on the abnormal aggregation or alteration of tau proteins, thereby contributing to the amelioration of AD-related pathological changes [33,36,82,83,84,85,86]