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Among them, protein kinase C (PKC), a family of protein kinase enzymes involved in various cellular mechanisms, has been shown to phosphorylate NRF2 at Ser40 in its Neh2 domain, disrupting the association with KEAP1 and promoting its activation [203, 204]
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Resveratrol reversed these effects by facilitating calcium ion transport and activating CaMKII, thus facilitating the repair of transzonal projections
Roth RP, Drew RT, Lo RJ, et al
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