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When injury occurs, this balance shifts to strongly elevate NOS2 expression specifically in healing contexts, channeling nitric oxide toward tissue repair

Key ways it appears to mimic or amplify natural gastrointestinal and tissue repair mechanisms observed in animal studies: Strongly upregulates angiogenesis through multiple pathways (VEGF, EGR-1, FAK-paxillin) in injured tissues, similar to the bodys own response during normal wound healing and tendon/ligament repair

Fatigue is a more persistent state of exhaustion that may not improve with rest and can affect physical and mental functioning

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This often settles with continued use and proper hydration

Among the screened natural products, we selected (-)-Vestitol and Salviolone, two compounds with reported therapeutic effects for diseases other than AD, for further experimental investigation