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Its cationic nature facilitates electrostatic interactions with the negatively charged mucus layer, thereby extending its retention time in the intestinal mucosa (184)

During this phase, some patients report: Reduced hunger between meals Earlier feelings of fullness when eating Decreased interest in snacking Mild nausea, which may temporarily reduce appetite further Weeks 4-8: After the first month, the dose is usually increased to 0.5 mg weekly

doi: 10.2527/2000.7841078x 84 MtayerS.SeiliezI.CollinA.DuchneS.MercierY.GeraertP

Why is our Gut Microbiome So Important