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In WT mice, both Cagrilintide and sCT significantly increased cFos expression in these hindbrain nuclei compared to vehicles, indicating activation of satiety-related pathways

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Control groups of mice were maintained on LD or WD and given sham (10 mL/kg body weight sterile saline) injections throughout the study (termed LD/LD-V, or LD control, and WD/WD-V, or WD control, groups

AOD-9604 (Anti-Obesity Drug 9604) is a synthetic peptide corresponding to amino acids 176191 of human growth hormone

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At the same time GHK modulates the activity of matrix metalloproteinases, interpreted in research as a balance between buildup and breakdown of the matrix (Pickart et al., 2015)