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The metabolism of vitamin B12 provides a protective system, such as gastric and hepatic R-proteins and IF, to avoid the utilization of bacteria

Hoppe Seylers Z Physiol Chem (1972) 353(2):2216

longer-term storage at -20C to -80C depending on institutional standards

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Mild possible glutathione side effects may include: Mild gastrointestinal discomfort Bloating Headache Allergic reactions (creams or serums) Intravenous glutathione carries the greatest risk, with serious adverse effects including liver toxicity, allergic reactions, and organ stress