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Color figures are included in the HTML version of this manuscript Additional information Edited by A Finazzi-Agro Supplementary Information accompanies the paper on Cell Death and Differentiation website ( Supplementary information Rights and permissions About this article Cite this article Franco, R., Cidlowski, J

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These brain regions are pivotal in regulating both emotional responses and cognitive functions, suggesting that estrogen, through ER and ER, plays a central role in supporting neural processes essential for memory formation, mood regulation, and decision-making [13] (Figure 1)