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The most appropriate treatment depends on factors including: medical history BMI weight-related health risks previous treatment response current medication personal preferences potential side effects clinical eligibility Semaglutide is injected under the skin rather than into a muscle or vein

However, supplementing with high doses of folic acid has been associated with adverse side effects

But a study by Canadian scientists published in Jama Ophthalmology has found that after six months of use GLP-1 RAs are associated with double the risk of older people with diabetes developing neovascular age-related macular degeneration compared with similar patients not taking the drugs

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