The first RCT to investigate the effect of liraglutide in patients with NAFLD was the LEAN study, in which 52 patients with NASH were randomized to either 48 weeks of treatment with liraglutide (1.8 mg/day) or placebo (66)
(Dermis) (Collagen) (Elastin) (Ceramide)
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Retatrutide: 2.5mg weekly, increasing to 5mg at week 3 Testosterone: 200mg weekly (split into two injections) Anavar: Not yet introduced Focus: Allow body to adjust to Retatrutide, establish testosterone baseline, dial in nutrition Retatrutide: 5mg weekly, increasing to 7.5mg at week 7 if tolerated Testosterone: 200mg weekly (split into two injections) Anavar: 20mg daily (10mg morning, 10mg evening) Focus: Maximize fat loss momentum while Anavar begins producing visible effects Retatrutide: 7.5mg to 10mg weekly based on response and tolerance Testosterone: 200mg weekly (split into two injections) Anavar: 30mg daily (15mg morning, 15mg evening) Focus: Push fat loss while strength and muscle quality improvements peak Retatrutide: Maintain or slightly reduce dose based on goal proximity Testosterone: 200mg weekly (split into two injections) Anavar: 30mg to 40mg daily based on response Focus: Final fat loss push, maximum definition, peak aesthetic result Retatrutide Titration Strategy Starting Retatrutide at lower doses and gradually increasing is essential
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The best way to offset this is through building muscle with exercise