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Their pleiotropic benefits arise from intricate signalling cascades that regulate appetite, insulin secretion, and energy homeostasis across multiple tissues

The cardiovascular indication for Wegovy, FDA-approved in March 2024 after the SELECT trial (Lincoff et al

Originally developed for type 2 diabetes, these drugs have now proven to be some of the most powerful tools for sustainable weight loss

The pathophysiology of obesity and sarcopenia is considered a multifaceted vicious cycle rather than a simple causal relationship [4]

Simplemente significa que, en ese momento, se est tratando con la medicacin

Even with recent advances in pharmacotherapy, many individuals continue to experience symptoms, particularly anhedonia, cognitive slowing or fatigue, and emotional instability [2], and up to one-third of patients develop treatment resistance [3]