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In vivo study showed that UA can induce autophagy, the primary process for clearing intraneuronal aggregated -synuclein, by inhibiting mTOR/ULK1 signaling in the midbrain of SNCA A53T transgenic mice

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Cell Physiol Biochem 12:373384 Bokori-Brown M, Petrov PG, Khafaji MA et al (2016) Red blood cell susceptibility to Pneumolysin: correlation with membrane biochemical and physical properties*

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Only 3 heterozygous carriers of the p.S539W allele were identified in the Family study participants

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