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Iron deficiency can cause anemia, fatigue, shortness of breath, and heart arrhythmias

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Mutations in the lipoyltransferase LIPT1 gene cause a fatal disease associated with a specific lipoylation defect of the 2-ketoacid dehydrogenase complexes

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Although the underlying mechanism for these gender effects is not known, some of the differences have been attributed to the levels of sex hormones and their receptors 76

It is a two ATP-requiring enzymatically catalyzed process.[] After its synthesis, glutathione gets distributed in intracellular organelles, including endoplasmic reticulum (ER), nucleus, and mitochondria.[] NUCLEAR GLUTATHIONE In the nucleus, GSH prevents the oxidation of sulfhydryl groups of several proteins to disulfide groups