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Resveratrol derivative excited postsynaptic potentiation specifically via PKC-NMDA receptor mediation

4.1.2 PI3K/AKT inhibitors Activation of phosphoinositide 3-kinase (PI3K) can lead to the phosphorylation and subsequent inactivation of Bad and caspase-9 [111]

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1 Introduction T2D is a complex and progressive metabolic disorder driven not only by insulin resistance but also by the gradual loss of pancreatic -cell functionality (Khunti et al., 2025), particularly after withdrawal of therapy, including metformin, insulin, and GLP-1 (Shoung et al., 2025)